Blar i forfatter "Rothe, Thomas"

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    • Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume 

      Popp, Ilinca; Rau, Alexander; Kellner, Elias; Reisert, Marco; Fennell, Jamina; Rothe, Thomas; Nieder, Carsten; Urbach, Horst; Egger, Karl; Grosu, Anca L.; Kaller, Christoph P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-19)
      Background and Purpose: With improved life expectancy, preventing neurocognitive decline after cerebral radiotherapy is gaining more importance. Hippocampal damage has been considered the main culprit for cognitive deficits following conventional whole-brain radiation therapy (WBRT). Here, we aimed to determine to which extent hippocampus-avoidance WBRT (HA-WBRT) can prevent hippocampal atrophy ...

    • Hippocampus-avoidance whole-brain radiation therapy with a simultaneous integrated boost for multiple brain metastases 

      Popp, Ilinca; Rau, Stephan; Hintz, Mandy; Schneider, Julius; Bilger, Angelika; Fennell, Jamina Tara; Heiland, Dieter Henrik; Rothe, Thomas; Egger, Karl; Nieder, Carsten; Urbach, Horst; Grosu, Anca-Ligia (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-06)
      <i>Background</i> - The current study was aimed at investigating the feasibility of hippocampus‐avoidance whole‐brain radiation therapy with a simultaneous integrated boost (HA‐WBRT+SIB) for metastases and at assessing tumor control in comparison with conventional whole‐brain radiation therapy (WBRT) in patients with multiple brain metastases.<p> <p><i>Methods</i> - Between August 2012 and December ...